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The Absorption Question: What the Research Actually Shows Here’s the standard story most people learn: B12 absorption requires intrinsic factor, a protein secreted in the stomach, which escorts B12 to specialized receptors in the ileum (the end of your small intestine)

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I’ve found that for most people with Hashimoto’s, a small intake of iodine (150-220 mcg daily) is usually safe and potentially helpful, although doses above that can be inflammatory