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By competitively binding to p53, FOXO4-DRI displaces endogenous FOXO4, causing p53 nuclear exclusion and translocation to mitochondria where it triggers the intrinsic apoptotic pathway through caspase-3/7 activation
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However, this use is based mostly on animal and lab studies, not confirmed human clinical trials, so it remains an off-label, non-standardized practice
Glutathione is a powerful antioxidant naturally made within the body
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