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They wrote: “For example, replacing the conserved glycine-101 with alanine (G101A) in petunia EPSPS weakens the Km(app) for PEP by 40-fold, reduces kcat by 2-fold, but perturbs glyphosate inhibition by nearly 5000-fold.” This would be expected if glyphosate works through substituting for glycine via the DNA code, which, with alanine substituted, no longer matches

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