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In rat models it accelerated healing of a transected Achilles tendon (Staresinic et al., 2003, J Orthop Res) and of the tendon to bone junction after detachment (Krivic et al., 2006, J Orthop Res), and a 2019 review (Gwyer et al., 2019, Cell Tissue Res) attributes these effects largely to nitric oxide pathway modulation and VEGF driven angiogenesis
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