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[DOI] [PMC free article] [PubMed] [Google Scholar] 78.Giacobbe J., Marrocu A., Di Benedetto M.G., Pariante C.M., Borsini A
East West Pharma
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634 AAK1 inhibitor LX-9211: Junctional protein 2-associated kinase 1 (AAK1) is widely expressed in the brain and spinal cord and is a viable target for the treatment of neuropathic pain, and BMS-986176/LX-9211 is a novel class of bis(iso)aryl ethers that are highly selective, CNS-permeable, and potent AAK1 inhibitors
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