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Abbreviations: AUC 0–6 hr area under the plasma concentration-time curve from time 0 to 6 hr AUC inf area under the plasma concentration-time curve from time 0 to infinity CDA cytidine deaminase C 0 initial plasma concentration at time 0 C max maximum plasma concentration dFdU 2’,2’-difluoro-2’-deoxyuridine Gem gemcitabine NT nucleoside transporters PEPT1 peptide transporter 1 THU tetrahydrouridine T 1/2 half-life T max time to reach the maximum plasma concentration V-Gem 5’-l-valyl-gemcitabine V ss volume of distribution steady-state Footnotes Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication
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Efficacy of intraoperative vein graft storage solutions in preserving endothelial integrity during coronary artery bypass surgery
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