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Body weights and blood glucose levels were monitored before the induction of diabetes and on days 0, 7, 14 and 21 respectively after the establishment of diabetes mellitus using the glucose oxidase method [12]
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However, oxidation of GSH to GSSG may contribute significantly to its depletion under conditions of excessive exposure to ROS or RNS and may be an important event during cytotoxic agent-induced apoptosis [25,26]
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