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Targeting oxidative stress as a preventive and therapeutic approach for cardiovascular disease | Journal of Translational Medicine | Springer Nature Link

Reported V max / K m values for the toxic N -acetyl cysteine S -conjugates of halogenated alkenes were generally similar to those of the N -acetyl derivatives of the l-aromatic amino acids but in a few cases considerably higher (Newman et al., 2007)

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Considering the quantity of exercise performed, untrained subjects are more susceptible to the negative consequences of increased oxidative stress, whereas trained individuals often have diminished effects due to higher oxidative tolerance (Figure 1)