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Biomarker-driven patient stratification Currently, the diagnosis of tinnitus relies almost entirely on subjective self-report, as no objective biomarker has been validated for clinical diagnosis or patient stratification

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Pantethine increased aldehyde dehydrogenase activity by as much as 71% 4 Acetaldehyde, the primary metabolite of alcohol, may promote alcohol addiction by combining with monamine metabolites to form addicting morphine-like alkaloids 1,2,3 Acetaldehyde has also been implicated in the pathogenesis of alcoholic liver disease and alcoholic cardiomyopathy and may play a role in the development of atherosclerosis as related to ethanol ingestion 4,5 References: Myer RD