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BBE31 from the Lyme disease agent Borrelia burgdorferi, known to play an important role in successful colonization of the mammalian host, shows the ability to bind glutathione - ScienceDirect
NF-κB Pathway NF-κB is a transcription factor regulating cell-to-cell interaction, intracellular communication, cell recruitment, and transmigration
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For instance, in M1 macrophages, disrupted Golgi function compromises system Xc - delivery to the plasma membrane, thereby limiting cystine uptake, depleting glutathione, and sensitizing cells to ferroptosis (112)
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