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In the retinal degeneration model of light-treated BALB/cJ mice, treatment with indole-3-carbinol diminished INOS and NO· released by microglia, while concomitantly increasing the levels of anti-oxidants gene NQO1 and HMOX1
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Lipid nano emulsions can be formed by the dispersion of an immisicible liquid in another stabilized emulsifying agent and can have particles of about 200 nm that are composed of the lipid, water, and surfactant that can contain the polynucleotide to be delivered (e.g., the engineered or non-naturally occurring composition (e.g., components of the trans-splicing system) polynucleotide(s) of the present invention)
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