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Species rate expressions, shown in equation (5–10), are therefore numerically integrated by using the IMSL (International Mathematical and Statistical Library) DIVPAG (double-precision initial value problem solver using either Adam-Moulton's or Gear's method) coded using Fortran [40–42]
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Mutation of the strictly conserved guiding bar residue Asn419′ hTrxR1 alone led to a strong effect (Table 2), rendering it the most important residue for aligning the flexible C-terminal arm during catalysis
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