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Vitamin B12 may also play an important role in bone health, as studies have shown that low blood levels of B12 can be associated with an increased risk of osteoporosis in women
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Zhao and colleagues reported that these peptides concentrated 1000-fold in the inner mitochondrial membrane, and that in neuronal N2A cells they potently reduced intracellular reactive oxygen species and cell death caused by t-butylhydroperoxide, with half-maximal effect concentrations in the nanomolar range
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