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Moreover, distinct cytokine signatures have been associated with varying severity levels of ME/CFS, where higher levels of plasma pro-inflammatory cytokines, such as colony-stimulating factor 2 (CSF2), correlate with increased physical and fatigue symptoms in these patients (Giloteaux et al., 2023)
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The muscles can relax by injecting a local anesthetic or a combination of anesthetics and anti-inflammatory medications directly into the trigger points, reducing pain and discomfort
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