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Engineered nanoplatforms for brain-targeted co-delivery of phytochemicals in Alzheimer's disease: Rational design, blood-brain barrier penetration, and multi-target therapeutic synergy - Neurotherapeutics
The study found that 2-methoxyestradiol elicited significant cytotoxicity (15%–25%) as a single agent, but the combination of both agents induced apoptosis more than twofold greater than by each compound alone
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DNA-dependent protein kinase (DNA-PK) is an important regulator of DNA damage response
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