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In the early 1950s, an epidemiological investigation at the Minamata district showed that several cats fed a diet that primarily consisted of fish presented a severe condition named “dancing disease”, which was characterized by movement disorders, convulsions and death (Kitamura et al., 1957)

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doi: 10.1016/j.jim.2014.03.021 26 KapoorPNathwaniNJelinekTPourLPerrotADimopoulosM-Aet al

producing components of the cell‚ resulting in reduced cellular metabolic activity‚ and the accumulation of cellular debris