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Furthermore, expression of SLC7A11, a GSTO1 and C1-27 target gene, was increased in C1-27 -treated tumours indicating target engagement (Fig
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Pancreatic cancer ACLY KO cells were then transduced with a retroviral pOZ-N vector (addgene 3781) expressing ACLY or an empty pOZ-N vector to generate cells with reconstituted ACLY (ACLY KO plus ACLY cDNA) or an empty vector (ACLY KO)
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