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Starting from an unbiased analysis of this context, it is noteworthy that the majority of PADs relies on colorimetric detection, despite the intrinsic limitations of this technology as low sensitivity, restricted linear ranges, color saturation problems, and background color due to the matrices ( The analytical potential of ePADs has been well-established in literature as customized tools, being able to overcome sensitivity and selectivity drawbacks, as well as to encompass multifarious configurations of sensors (e.g., screen-printed electrodes), bioreceptors (e.g., enzymes, antibodies, artificial molecules), and nanomaterials (e.g., metal nanoparticles, graphene, carbon black) ( In a recent review, Currently, ePAD applications include clinical diagnosis, environmental monitoring, food analysis, and drug analysis

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