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Transfection studies demonstrate that GSH deficiency causes increased oxidative stress, downregulation of VDBP /VD-25-hydroxylase/ VDR , and upregulation of CYP24A1 in mouse hepatocytes and downregulation of PGC-1α, VDR, GLUT4 in mouse myotubes, similar to results seen in HFD-fed mice
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Several trials are currently underway that will shape the future of AHF care [237]
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