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DHCR24 is the final enzyme in the biosynthesis pathway of cholesterol, a ubiquitous molecule that serves as a precursor to several by-products participating in a wide variety of physiological and pathological pathways, such as the metabolism of lipids and vitamin D, the synthesis of steroid hormones, and liver X-receptor (LXR)/retinoid X-receptor (RXR) activation, among others (Warren et al., 2021)
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Glycosaminoglycans increase when extracellular matrix water and/or salt increases
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