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Additionally, STING inhibitors (e.g., C-176) have been employed to interfere with the cGAS/STING pathway activated by mtDNA leakage [71], while TLR4 antagonists (such as TAK-242) block immune activation induced by saturated fatty acids and other DAMPs [100]

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Figure 1 Given the current aging population, there will be a progressive rise in the number of PD sufferers in China