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did a meta-analysis on the effect of NAC 1200 mg/day, carbocisteine 1500 mg/day, and erdosteine 600 mg/day on chronic obstructive pulmonary disease and found erdosteine to be superior in efficacy, compared to NAC and carbocisteine [184]
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TLR4 is one such PRR that detects damage-associated molecular patterns (DAMPs) created by stressed and dying cells and pathogen-associated molecular patterns (PAMPs) like bacterial lipopolysaccharide (LPS) (Guo et al., 2022
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