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(2006) have presented a new model for the catalytic reaction in which Glu146 functions as a general base, accepting a proton from zinc-bound water and shuttling the proton to the leaving group facilitating breakdown of the tetrahedral intermediate
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[DOI] [PMC free article] [PubMed] [Google Scholar] 151.Salari N, Khodayari Y, Hosseinian-Far A, Zarei H, Rasoulpoor S, Akbari H, et al
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