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While the arachnoid barrier and the BCSFB have moderate permeability in the fetal, neonatal, and adult period, the BBB is the closest structure to the brain cells and hence, is considered the most important barrier (Benz and Liebner, Figure 1)
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In December 2025, 10 groups of peptides available in New Zealand were classified as prescription medicines (including MOTS-C, a peptide used to regulate metabolism) after a recommendation issued by Medsafe’s Medicine Classification Committee in mid-July
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