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The poisoning of the environment with HMs is mostly caused by intensive mining operations, fast industrialization, and widespread agricultural activities (El-Sappah et al., 2021a
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Stable expression of a Cas9-resistant silent point mutant MTHFD2 cDNA (MTHFD2 R ) restored cell proliferation in MTHFD2 KO LCLs (Figures 4E and 4F), confirming the role of MTHFD2 in promoting LCL growth and survival
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