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And the other thing about multiple myeloma is when we think about where these cells are, they're grown in that soft tissue, which you can see on the slide there, in the middle of the bone, but the myeloma cells can also interact with the hard part of the bone, and that's called the cortical part

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Adequate protein intake, biotin supplementation, and avoiding excessively rapid weight loss (more than 2-3 pounds per week) reduce the risk