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GIRGL promotes cell cycle-associated protein 1 (CAPRIN1)-mediated liquid-liquid phase separation, leading to the formation of stress granules that suppress the translation of glutaminase 1 (GLS1) messenger RNA (mRNA)
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En la misma forma el ácido alfa-cetoglutárico, metabolito importante en el citado ciclo de Krebs, es transformado en succinato activo y luego en ácido succínico, pivote fundamental en dicho ciclo
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