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Mechanism of Action Inhibits Nicotinamide N-Methyltransferase (NNMT) Increases intracellular nicotinamide and NAD⁺ levels Improves mitochondrial efficiency and energy metabolism Supports lipolysis and fat oxidation Reduces adipocyte (fat cell) growth and proliferation Modulates inflammatory pathways and insulin signaling These effects may lead to enhanced fat metabolism, better blood sugar regulation, improved endurance, and a general increase in metabolic flexibility

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It is important to recognize that in these publications, pathologists often used words like “inflammation”, “fat necrosis”, and “fibrosis” as descriptors of histology, but these findings may differ from the actual biochemical processes that precisely define these terms