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combined PEGylation with thiolated chitosan: PEGylation helps the carrier cross the mucus layer, while positively charged thiolated chitosan enhances mucoadhesion and locally inhibits P-gp, thereby significantly improving the intestinal absorption rate of amikacin
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In this regard, one of the potential functions of extracellular GSH is a source of both Cys and Met in the overall sulfur-containing amino acid balance
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