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(2004) provided experimental data to show that the contribution of the alternative reaction for cystathionine synthesis increased as substrate concentrations increased: the alternative reaction with Cys accounted for 23% of total cystathionine synthesis when all substrates were present at 0.1 mM, 35% when substrates were present at 1 mM, and 44% when substrates were present at 10 mM

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